Persistent Pain 12 Months After Myocardial Infarction: Does It Predict 8-Year Mortality Risk?
Persistent pain at 12 months after myocardial infarction (MI) has emerged as an important but often underappreciated clinical finding in long-term cardiovascular care. While acute survival after MI has improved dramatically due to early reperfusion strategies, evidence-based pharmacotherapy, and structured secondary prevention, a growing number of survivors continue to report ongoing pain one year after the index event. This observation raises a critical clinical question: does persistent post-MI pain signal a higher risk of long-term mortality, particularly over an eight-year follow-up period? In recent years, attention has shifted from short-term survival to long-term outcomes, functional recovery, and quality of life among MI survivors. Persistent pain—most commonly chest pain but also including musculoskeletal discomfort, neuropathic symptoms, or diffuse bodily pain—poses a diagnostic and prognostic challenge. Clinicians must determine whether such pain represents ...